SINGAPORE – As veterinary medicine advances, pets are living longer lives. This means that they spend a significant part of their lives in old age.
This increased longevity brings a new challenge: dementia, also known as cognitive dysfunction syndrome (CDS), a serious condition involving age-related cognitive decline.
Pet dementia is remarkably similar to Alzheimer’s in humans.
As pets age, the capacity of the body’s natural repair and defence mechanisms is reduced, leading to the accumulation of toxic substances (free radicals and oxygen reactive species). This “oxidative stress” damages brain cells.
The brain begins to accumulate a sticky protein called amyloid plaques. These plaques act like roadblocks between brain cells, preventing the sending and receiving of signals correctly.
The outcome is a severe set of distressing behavioural changes that reflects the loss of mental and social function. CDS is a fundamental quality-of-life concern for both pets and their owners.
Pet dementia is an unspoken crisis. Published studies indicate that 14 to over 70 per cent of dogs aged eight and older suffer from some level of cognitive decline.
In cats, the numbers are even more striking, with roughly one-third of cats aged 11 to 14 showing signs, with numbers increasing to 50 per cent for cats over the age of 15.
Despite these high numbers, there is a significant disparity between the number of pets suffering from the disease and those receiving effective treatment.





