Wegovy weight-loss pills vs injections: How do they compare and why you shouldn’t buy the pills online?

Conversely, there are also patients who haven’t opted for GLP-1 RA medications, he said. “The patient’s target weight as well as usage duration are considerations. If it is just for short term use, phentermines or orlistat can be considered instead.” Another factor is cost “because GLP-1 RA tend to be more expensive”, said Dr Yeo. A month’s supply of Ozempic shots, for instance, can cost around S$400 or more.

WHAT ABOUT THE SIDE EFFECTS?

Whether injected or ingested, GLP-1 RAs can cause side effects, mainly gastrointestinal symptoms such as nausea, vomiting, bloating, constipation or diarrhoea, said Dr Ho. “These side effects are common. But they can be mitigated by gradual dose escalation and they usually improve over time.”

Even with those measures in place, Dr Ng highlighted that GLP-1 RA medications are not for everyone. “We are particularly cautious with people with previous pancreatitis, significant gastrointestinal disease, severe kidney or liver problems, pregnancy, and certain other medical conditions. The decision should, therefore, be made after a proper medical assessment.”